题目:Mesenchymal Stromal Cells: From Regeneration to Cancer
主讲人:Guangwen Ren, Assistant Professor,The Jackson Laboratory, Bar Harbor, Maine, USA
主持人:龚瑶琴 教授
时间:4月18日(周二)下午15:30
地点:趵突泉校区教学6楼3层6320 会议室
主讲人简介:
Dr. Ren本科就读于山东大学生命科学学院,2009年于美国Rutgers University获得免疫学博士学位,然后在Rutgers University和Princeton University从事博士后研究,2016年11月作为PI就职于The Jackson Laboratory。Dr. Ren的研究集中在间充质干细胞在免疫抑制和肿瘤微环境中的作用。
Selected Publications:
1. Ren G, Zheng H, Shen M, Peng J, Jiang Y, Liu Y, Wei Y, Smith HA, Zheng B, Wu H, Schiff D, Shao C, Haffty B, and Kang Y. Mesenchymal stromal cells play a critical role in cancer resistance to radiotherapy. 2016. Submitted.
2. Ren G, Zhao X, Zheng B, Zheng H, Liu Y, Shen M, Sun G, Kane-Goldsmith N, Zhang C, Guo H, Liang L, Wei JJ, Qu X, Yang Q, Shi Y, Tischfiled JA, Kang Y* and Shao C*. Interferon-gamma and Kit Ligand Drive Tumor-associated Splenic Myelopoiesis. 2016. Submitted.
3. Ren G, Esposito MB, Kang Y. Bone metastasis and the metastatic niche. Journal of Molecular Medicine (invited review). J Mol Med (Berl). 2015 Nov;93(11):1203-12.
4. Ren G*, Liu Y*, Zhao X, Zheng B, Yuan Z, Zhang L, Qu X, Tischfield JA, Shao C and Shi Y. Tumor Resident Mesenchymal Stromal Cells Endow Naïve Stromal Cells with Tumor-promoting Properties. Oncogene, 2014 Jul 24;33(30):4016-20.
5. Ren G, Kang Y. A one-two punch of miR-126/126* against metastasis (news and views). Nature Cell Biology. 2013 Mar 1;15(3):231-3.
6. Ren G, Zhao X, Wang Y, Zhang X, Chen X, Xu C, Yuan ZR, Roberts AI, Zhang L, Zheng B, Wen T, Han Y, Rabson AB, Tischfield JA, Shao C, Shi Y. CCR2-Dependent Recruitment of Macrophages by Tumor-Educated Mesenchymal Stromal Cells Promotes Tumor Development and Is Mimicked by TNFα. Cell Stem Cell. 2012 Dec 7;11(6):812-24. Editorial by: Mantovani A. Cell Stem Cell. 11:730-32. 2012.